Coursework
Skills
Literature review, cancer biology, tissue engineering, stem cell, biosensor, business in biotech, presentation, team work
Project Duration
Undergraduate and MS
A Recombinant Collagen Scaffold to Deliver Oral Mucosa Epithelial Cells and Angiostatin for Treating Severe Bilateral Limbal Stem Cell Deficiency
Project for BENG 241A where we hypothesized that using a collagen scaffold to deliver a safe and effective dose of an anti-angiogenic factor, Angiostatin, will help overcome invasive corneal neovascularization post- transplantation of OMECs. The collagen scaffold with OMECs and angiostatin will be implanted in a mouse model of LSCD and in vivo corneal regeneration, transparency and neovascularization will be assessed to evaluate the success of the engineered scaffold.
An electrochemical novel biosensor for combinatorial sensing of two long non-coding RNA biomarkers for Hepatocellular Carcinoma
Project for BENG 230A where we hypothesized that a novel combinatorial approach of using two biomarkers would help enhance the efficiency of existing lncRNA biosensors for HCC which can currently only detect one biomarker at a time.
Biosensor to detect oil rancidity
Designed (theoretically) an enzyme-based POC biosensor for detection of cooking oil oxidative rancidity to determine its reusability threshold. Identified substrate present in oxidized oil by GC-MS technique, and subsequently the enzyme for its detection.
Incorporated the enzyme as bio-analyte into a biosensor technology, and compared its efficiency with other available analysis such as peroxide values, viscosity and saponification measurements.
Business model for a ready-tech automated bioreactor
Worked in a team to identify a tangible and tractable problem in biotech, and created a fast exit venture plan for it: an automated bioreactor for stem cell media replenishment
Identified an early adopter customer in our university itself, solution with ready-tech components and easily available intellectual property to protect it.